Opportunity Information: Apply for CDC RFA DP 23 0005
The Innovative Cardiovascular Health Program (CDC RFA DP 23 0005) is a CDC-funded cooperative agreement designed to strengthen and modernize how health systems prevent, detect, and manage two major cardiovascular disease (CVD) risk factors: high blood pressure (hypertension) and high blood cholesterol (hypercholesterolemia). The opportunity centers on practical, health system-based interventions that can be implemented across clinical settings, with an emphasis on improving continuity of care and ensuring patients do not fall through the cracks as they move between primary care, specialty care, pharmacies, hospitals, and community-based services. The overall goal is to improve prevalence awareness, detection, and control of these conditions, particularly in priority populations that experience disproportionate burden and worse outcomes.
A key feature of the program is its focus on aligning care with national guidelines and evidence-based recommendations, then translating those recommendations into everyday clinical workflows. Applicants are encouraged to design approaches that make maximal use of electronic health record (EHR) data, such as building or refining clinical decision support tools, implementing population health registries, improving patient identification and outreach, and tracking control rates over time. The program also highlights technological advances that can improve medication adherence, which may include digital tools, remote monitoring, pharmacy-based supports, refill synchronization, and other strategies that help patients start and stay on prescribed therapies. Another major emphasis is fully utilizing community health workers and similar frontline roles to strengthen patient follow-up, coaching, navigation, and connection to community resources, with the intent of building strong community-clinical linkages and durable partnerships.
This funding opportunity explicitly builds on lessons learned and advances from an earlier CDC initiative (CDC-RFA-DP18-1817), signaling that the CDC is looking for the next phase of innovation and scale. The program is not only about clinical metrics; it also prioritizes addressing broader drivers of cardiovascular risk and poor control, including social determinants of health (SDoH), stress and mental health, health inequity, and injustice. In practice, that means applicants are expected to incorporate strategies that recognize and reduce barriers like limited access to healthy foods, unstable housing, transportation challenges, cost-related medication nonadherence, lack of culturally responsive care, chronic stress, and the cumulative effects of structural inequities. The intent is to improve outcomes by pairing clinical improvements with real-world supports that make healthier choices and consistent care more feasible.
Administratively, this is a discretionary grant awarded as a cooperative agreement, which typically means there is substantial federal involvement and ongoing collaboration between CDC and awardees during implementation. The sponsoring agency is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, specifically within NCCDPHP. The opportunity was created on March 23, 2023, with an original application deadline of May 23, 2023, and electronic submissions were required by 11:59 pm ET on the due date. The award ceiling is $1,200,000, and CDC anticipated making about 12 awards, indicating a competitive national program aimed at supporting a limited number of well-positioned entities to implement and demonstrate impactful approaches.
Eligibility is broad, reflecting CDCs interest in cross-sector collaboration and scalable models. Eligible applicants include state, county, and local governments; special districts; independent school districts; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions in those categories); for-profit entities (including small businesses); and other entities as described in the full eligibility clarification. Overall, the program is structured to fund organizations that can convene partners, use data effectively, implement evidence-based hypertension and cholesterol management strategies, and intentionally reduce inequities by addressing both clinical quality and the upstream conditions that shape cardiovascular health.Apply for CDC RFA DP 23 0005
- The Department of Health and Human Services, Centers for Disease Control - NCCDPHP in the health sector is offering a public funding opportunity titled "The Innovative Cardiovascular Health Program" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.426.
- This funding opportunity was created on Mar 23, 2023.
- Applicants must submit their applications by May 23, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,200,000.00 in funding.
- The number of recipients for this funding is limited to 12 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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| Delta Health Systems Implementation Program Apply for HRSA 23 128 Funding Number: HRSA 23 128 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $404,000 |
| Cooperative Agreement for the Hispanic/Latino Behavioral Health Center of Excellence Apply for FG 23 002 Funding Number: FG 23 002 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,125,000 |
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| WISEWOMAN: Well-Integrated Screening and Evaluation of WOMen Across the Nation Apply for CDC RFA DP 23 0003 Funding Number: CDC RFA DP 23 0003 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $2,000,000 |
| American Indian and Alaska Native Behavioral Health Center of Excellence Apply for FG 23 001 Funding Number: FG 23 001 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,500,000 |
| Treatment, Recovery, and Workforce Support Grant Apply for TI 23 021 Funding Number: TI 23 021 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $500,000 |
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| Recovery Community Services Program Apply for TI 23 018 Funding Number: TI 23 018 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $300,000 |
| Addressing Dementia in Indian Country: Models of Care Apply for HHS 2023 IHS ALZ 0001 Funding Number: HHS 2023 IHS ALZ 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Health Funding Amount: $200,000 |
| National Partnerships to Promote Cancer Surveillance Standards and Support Data Quality and Operations of National Program of Cancer Registries Apply for CDC RFA DP 23 0008 Funding Number: CDC RFA DP 23 0008 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $5,975,000 |
| CDC’s National Networks Driving Action: Preventing Tobacco- and Cancer-Related Health Disparities by Building Equitable Communities Apply for CDC RFA DP 23 0015 Funding Number: CDC RFA DP 23 0015 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: Case Dependent |
| Health Promotion and Disease Prevention Research Centers: RFA-DP-24-004 Apply for RFA DP 24 004 Funding Number: RFA DP 24 004 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $1,000,000 |
| Screening and Treatment for Maternal Mental Health and Substance Use Disorders Apply for HRSA 23 085 Funding Number: HRSA 23 085 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $750,000 |
| Strategic Prevention Framework – Partnerships for Success for States Apply for SP 23 003 Funding Number: SP 23 003 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $1,250,000 |
| Strategic Prevention Framework – Partnerships for Success for Communities, Local Governments, Universities, Colleges, and Tribes/Tribal Organizations Apply for SP 23 004 Funding Number: SP 23 004 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $375,000 |
| Assuring Comprehensive Perinatal, Maternal and Infant Health and the Elimination of Perinatal HIV in the United States Apply for CDC RFA PS23 0013 Funding Number: CDC RFA PS23 0013 Agency: Department of Health and Human Services, Centers for Disease Control - NCHHSTP Category: Health Funding Amount: Case Dependent |
| Strengthening Public Health Systems and Services in Indian Country Apply for CDC RFA TO 23 0001 Funding Number: CDC RFA TO 23 0001 Agency: Department of Health and Human Services, CENTERS FOR DISEASE CONTROL CSTLTS Category: Health Funding Amount: Case Dependent |
| Global Emergency Response and Recovery Partner Engagement: Expanding Efforts and Strategies to Improve Rapid Response to Public Health Emergencies Globally Apply for CDC RFA GH 23 0042 Funding Number: CDC RFA GH 23 0042 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Community Health Equity through Systems Strengthening (CHESS) Apply for CAM RFI 00001 Funding Number: CAM RFI 00001 Agency: Agency for International Development, Ghana USAID-Accra Category: Health Funding Amount: $2,000,000 |
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