Opportunity Information: Apply for PA 18 676
This NIH funding opportunity (PA 18-676) was issued by the Office of Research on Womens Health (ORWH) as a one-year administrative supplement program meant to add targeted work onto existing, active NIH parent grants. The central aim is to strengthen research on the health of women from U3 populations, meaning groups that have historically been understudied, underrepresented, and underreported in biomedical research. Rather than funding entirely new standalone projects, these supplements are designed to expand or accelerate ongoing NIH-supported research so it more directly addresses health disparities affecting women in the United States.
The scientific emphasis is on understanding how sex and gender influences interact with social determinants of health to shape disease risk, health outcomes, and access to prevention and treatment. The announcement explicitly calls for interdisciplinary, transdisciplinary, or multidisciplinary approaches, and it allows a broad range of study types, including preclinical, clinical, and behavioral research (clinical trials are optional). Applicants are expected to focus on the intersection of sex/gender with factors such as race and ethnicity, socioeconomic status, education, health literacy, gender identity, and whether someone lives in an urban or rural setting. The idea is not simply to compare groups, but to examine how these overlapping factors jointly influence health behaviors, screening uptake, treatment access, and therapeutic outcomes for women.
A key requirement is alignment with Objective 3.9 under Goal 3.0 of the NIH Strategic Plan for Research on Womens Health. That objective specifically prioritizes examining health disparities among women that arise from differences in race/ethnicity, socioeconomic status, gender identity, and urban-rural living, and how those differences affect health, behaviors, and access to screening and treatment. In practical terms, a competitive supplement would clearly tie its aims to disparity mechanisms or disparity-reducing interventions relevant to women, and explain why the added work is best accomplished as a supplement to the existing parent award within a one-year window.
Projects must include a focus on one or more NIH-designated health disparities populations. The opportunity lists these populations as Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities (SGM). The program also encourages studies that consider overlapping identities and conditions, such as socioeconomically disadvantaged SGM women or rural women from specific racial and ethnic groups. This emphasis reflects the program’s broader theme of intersectionality, where multiple social determinants combine to influence risk and access in ways that are often missed when populations are studied in isolation.
In terms of who can apply, the eligible applicant landscape is wide and includes many common NIH applicant types: state, county, city, township, and special district governments; independent school districts; public and state-controlled universities; private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and certain tribal governments and tribal organizations. The announcement also highlights additional eligible applicant categories often central to serving disparity populations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). Faith-based and community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions are also included among eligible applicants.
At the same time, the opportunity draws firm boundaries around foreign involvement. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined in NIH policy) are not allowed. The practical takeaway is that the supported work must be fully domestic and carried out within eligible U.S.-based organizational structures.
The funding instrument is a discretionary grant in the form of an administrative supplement, with an award ceiling listed at $200,000. The original closing date for the opportunity was April 16, 2018, and the program was created on February 22, 2018. The listing is associated with multiple CFDA numbers (now commonly referred to under Assistance Listings), reflecting that supplements could attach to a variety of NIH institute and center parent awards that fall under different NIH program authorities.
Overall, this opportunity was built to push existing NIH-funded projects to more directly and rigorously address womens health disparities by adding near-term, one-year work that integrates sex/gender considerations with real-world social determinants and NIH-recognized health disparity populations. The program’s intent is both scientific and practical: improve the evidence base on womens health in groups too often missing from research, and generate findings that can inform better screening, prevention, and treatment access for women experiencing structural and social barriers to health.Apply for PA 18 676
- The National Institutes of Health in the education, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations An ORWH FY18 Administrative Supplement (Admin Supp - Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.173, 93.242, 93.273, 93.279, 93.313, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.846, 93.847, 93.855, 93.865, 93.867.
- This funding opportunity was created on 2018-02-22.
- Applicants must submit their applications by 2018-04-16. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is NIH PA 18-676?
PA 18-676 is an NIH funding opportunity issued by the Office of Research on Womens Health (ORWH) to support a one-year administrative supplement. It is designed to add targeted, women-focused health disparities work onto an existing, active NIH parent grant rather than funding a brand-new standalone project.
Is this opportunity meant to fund a new research project?
No. This program is specifically an administrative supplement intended to expand, enhance, or accelerate research that is already supported by an active NIH parent award. The added work should be feasible within a one-year period and clearly justified as an add-on to the existing project.
What is the main goal of this administrative supplement?
The central aim is to strengthen research on the health of women from U3 populations (groups historically understudied, underrepresented, and underreported in biomedical research), with an emphasis on womens health disparities in the United States.
What does the opportunity mean by U3 populations?
U3 refers to populations that have historically been understudied, underrepresented, and underreported in biomedical research. The supplement is intended to help correct these gaps by ensuring ongoing NIH-funded work more directly addresses womens health needs and disparities in these groups.
What kinds of research does this supplement support?
The announcement allows a broad range of research, including preclinical, clinical, and behavioral studies. Interdisciplinary, transdisciplinary, or multidisciplinary approaches are explicitly encouraged. Clinical trials are optional.
Are clinical trials required?
No. Clinical trials are optional under this opportunity.
What is the scientific emphasis of PA 18-676?
The scientific focus is on how sex and gender influences interact with social determinants of health to shape disease risk, health outcomes, and access to prevention and treatment for women. The intent is to go beyond simple comparisons and examine how overlapping factors jointly influence outcomes and access.
Which social determinants of health are highlighted in the opportunity?
The opportunity calls for attention to the intersection of sex/gender with factors such as race and ethnicity, socioeconomic status, education, health literacy, gender identity, and whether someone lives in an urban or rural setting.
Does the program expect an intersectional approach?
Yes. The announcement emphasizes intersectionality, meaning proposals should examine how multiple, overlapping identities and conditions combine to influence health risk, health behaviors, screening uptake, treatment access, and therapeutic outcomes for women.
What specific NIH strategic plan objective must the supplement align with?
Projects must align with Objective 3.9 under Goal 3.0 of the NIH Strategic Plan for Research on Womens Health. This objective prioritizes examining womens health disparities arising from differences in race/ethnicity, socioeconomic status, gender identity, and urban-rural living, and how these differences affect health, behaviors, and access to screening and treatment.
What does alignment with Objective 3.9 look like in practice?
Based on the announcement, a competitive supplement would clearly connect its added aims to either disparity mechanisms (how disparities arise and are sustained) or disparity-reducing interventions relevant to women, and explain why the work is best done as a one-year supplement to the existing parent award.
Do projects have to include NIH-designated health disparities populations?
Yes. Projects must focus on one or more NIH-designated health disparities populations identified in the opportunity.
Which NIH-designated health disparities populations are listed?
The opportunity lists: Blacks/African Americans; Hispanics/Latinos; American Indians/Alaska Natives; Asian Americans; Native Hawaiians and other Pacific Islanders; socioeconomically disadvantaged populations; underserved rural populations; and sexual and gender minorities (SGM).
Does the opportunity encourage studying overlapping identities (for example, rural and SGM)?
Yes. The program encourages consideration of overlapping identities and conditions, such as socioeconomically disadvantaged SGM women or rural women from specific racial and ethnic groups, reflecting the stated emphasis on intersectionality.
Who is eligible to apply?
Eligibility is broad and includes many common NIH applicant types, such as state/county/city/township/special district governments; independent school districts; public and state-controlled universities; private institutions of higher education; nonprofits (501(c)(3) and non-501(c)(3)); for-profit organizations (other than small businesses); small businesses; and certain tribal governments and tribal organizations.
Are minority-serving institutions specifically called out as eligible?
Yes. The opportunity highlights eligibility for institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI).
Are community-based and faith-based organizations eligible?
Yes. The announcement includes faith-based and community-based organizations among eligible applicants.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among eligible applicants.
Are foreign institutions or non-U.S. entities eligible to apply?
No. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply under this opportunity.
Can a U.S. organization apply if the project includes a non-domestic component?
No. Non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined in NIH policy) are not allowed. The work supported by this supplement must be fully domestic.
What is the funding mechanism and maximum award amount?
The funding instrument is a discretionary grant provided as an administrative supplement. The listed award ceiling is $200,000.
How long is the supplement period?
The supplement is designed as a one-year administrative supplement.
When was this opportunity created, and what was the original closing date?
The opportunity was created on February 22, 2018, and the original closing date was April 16, 2018.
Why are multiple CFDA (Assistance Listing) numbers associated with this opportunity?
The listing is associated with multiple CFDA numbers (now commonly referred to as Assistance Listings) because the supplements could attach to parent awards across multiple NIH Institutes and Centers operating under different NIH program authorities.
What is the practical purpose of this program for womens health research?
The program is intended to push existing NIH-funded projects to more directly and rigorously address womens health disparities by adding near-term work that integrates sex/gender considerations with real-world social determinants of health and NIH-recognized health disparity populations. The goal is to improve the evidence base and produce findings that can inform better screening, prevention, and treatment access for women facing structural and social barriers to health.
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