Opportunity Information: Apply for HT942524PRCRPPWSA
The DoD Peer Reviewed Cancer Research Program (PRCRP) Patient Well-Being and Survivorship Award (PWSA) is a Department of the Army (USAMRAA) grant opportunity designed to fund innovative, patient-centered cancer research that directly improves how people live during and after cancer. The program focuses on survivorship gaps that are often under-addressed in traditional cancer research, especially the day-to-day realities of physical function, quality of life, symptom burden, psychosocial strain, and cognitive challenges that can follow diagnosis and treatment. Projects must align with at least one FY24 PRCRP Topic Area and must address one or more core issues such as preservation of physical function, symptom management, resilience, neurocognitive deficits, decision-making, and psychosocial support for patients and those close to them (including family members and caregivers).
A major emphasis of this award is impact on real-world outcomes. The PWSA is not meant for incremental work or purely exploratory ideas without a clear pathway to changing care or survivorship outcomes. Applicants are expected to show how their study could meaningfully transform patient well-being in a way that connects back to one or more FY24 PRCRP Topic Areas. The intent is to push research that challenges existing assumptions about survivorship and patient care, and to speed the movement of promising approaches into settings that can affect clinical practice. The mechanism allows for translational or clinical research, including pilot clinical trials, as long as the work remains clearly tied to patient well-being and survivorship improvements rather than basic disease biology.
The types of projects that fit well under this opportunity include studies on maintaining or restoring function, improving quality of life and emotional well-being, and reducing symptoms across the full cancer experience, from active treatment through long-term survivorship. Competitive applications may examine topics like treatment toxicity and supportive care strategies, psychological distress and anxiety, palliative or supportive care interventions, educational or decision-support tools, and approaches that address cognitive issues linked to cancer or its therapies. The opportunity also encourages research on how behavioral and social functioning relates to cancer initiation, progression, detection, treatment, and rehabilitation, including studies aimed at improving mental health and cancer-related outcomes in defined populations. The overarching theme is evidence-based, patient-relevant interventions and surveillance methods that can identify psychosocial outcomes and improve survivorship care.
The PWSA expects applicants to present a clear, well-justified study design. Proposals must spell out the overall architecture of the research approach, whether it is interventional, descriptive, correlational, field experimental, retrospective or prospective, or even a meta-analysis. Study populations must be clearly defined, and the design must be supported with an appropriate statistical rationale that matches the research question. If questionnaires or survey tools are used, they need to be described in enough detail to support how results will be interpreted and why the measures are appropriate for the target population and outcomes. In other words, reviewers are looking for studies that are not only meaningful, but also methodologically strong and interpretable.
Preliminary data expectations depend on whether the project includes active recruitment of human subjects. If an application proposes prospective recruitment for a pilot clinical trial, preliminary data are required. For studies that do not involve active recruitment, preliminary data are not strictly required, but the proposal still needs a strong foundation, supported by solid reasoning and relevant literature, to show the approach is credible and likely to yield informative results.
A distinctive and non-negotiable element of this award is patient advocate participation. Every application must include at least one cancer patient advocate as an integral member of the research team, not as a symbolic addition. The advocate should be connected to a cancer advocacy organization, knowledgeable about current cancer issues, and aligned with the FY24 PRCRP Topic Area(s) being studied. The advocate can be someone living with cancer, a survivor with no evidence of disease, or a family member/caregiver. Their involvement is expected to be active and continuous across planning and implementation, including shaping the research question, influencing study design, participating in oversight, and contributing to evaluation and interpretation. The program explicitly signals that periodic attendance at meetings is not enough; the advocate role should be embedded into the project so that patient priorities and practical impact remain central throughout.
Just as important as what the PWSA funds is what it does not fund. Basic laboratory studies are considered outside the scope of this mechanism and may be withdrawn from consideration. The same applies to studies using animal models, which are not supported under this opportunity. The award is oriented toward human-relevant survivorship research and patient well-being outcomes, with a clear line of sight to improving care, services, or support systems.
From an administrative standpoint, this is a discretionary grant (CFDA 12.420) offered by the Department of the Army via USAMRAA under the PRCRP. Eligibility is listed as unrestricted. The opportunity number is HT942524PRCRPPWSA, with an original closing date of July 26, 2024. The anticipated number of awards is six, and the award ceiling is not specified in the provided source details.Apply for HT942524PRCRPPWSA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Peer Reviewed Cancer, Patient Well-Being and Survivorship Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2024-05-01.
- Applicants must submit their applications by 2024-07-26. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted.
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FAQs: DoD PRCRP Patient Well-Being and Survivorship Award (PWSA)
What is the PRCRP Patient Well-Being and Survivorship Award (PWSA)?
The Patient Well-Being and Survivorship Award (PWSA) is a Department of the Army (USAMRAA) funding opportunity under the DoD Peer Reviewed Cancer Research Program (PRCRP). It supports innovative, patient-centered cancer research that is designed to directly improve how people live during and after cancer.
Which agency is offering this grant?
This is a discretionary grant offered by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA), under the PRCRP.
What is the opportunity number for this award?
The opportunity number is HT942524PRCRPPWSA.
What is the CFDA number for this program?
The CFDA listing provided is 12.420.
What is the main purpose of the PWSA?
The main purpose is to fund research that produces real-world improvements in patient well-being and survivorship outcomes, especially in areas that may be under-addressed in traditional cancer research (for example: day-to-day physical function, quality of life, symptom burden, psychosocial strain, and cognitive challenges after diagnosis and treatment).
What kinds of survivorship issues does the PWSA prioritize?
The award emphasizes survivorship gaps affecting daily life and functioning, including physical function, quality of life, symptom burden, psychosocial strain, and cognitive challenges that may follow diagnosis and treatment.
Do projects have to align with specific PRCRP topics?
Yes. Projects must align with at least one FY24 PRCRP Topic Area and must connect the proposed work to patient well-being and survivorship improvements within that topic area framework.
What core issues can a project address under this award?
Projects must address one or more core issues such as preservation of physical function, symptom management, resilience, neurocognitive deficits, decision-making, and psychosocial support for patients and those close to them (including family members and caregivers).
Is the PWSA intended for basic research on cancer biology?
No. The PWSA is oriented toward human-relevant survivorship research and outcomes related to patient well-being. Basic disease biology work is not the emphasis of this mechanism.
Are basic laboratory studies allowed?
No. Basic laboratory studies are considered outside the scope of this mechanism and may be withdrawn from consideration.
Are animal studies allowed under this opportunity?
No. Studies using animal models are not supported under this opportunity.
What types of research designs are acceptable?
Proposals must present a clear and well-justified study design. The opportunity indicates that designs may include interventional, descriptive, correlational, field experimental, retrospective or prospective approaches, or even a meta-analysis, as long as the work is clearly tied to patient well-being and survivorship improvements.
Does the PWSA support translational or clinical research?
Yes. The mechanism allows translational or clinical research, including pilot clinical trials, provided the work remains clearly tied to improving patient well-being and survivorship outcomes rather than focusing on basic disease biology.
Does the PWSA support pilot clinical trials?
Yes. Pilot clinical trials are allowed under this mechanism as long as the trial is clearly aimed at improving patient well-being and survivorship outcomes.
What kinds of projects are a good fit for the PWSA?
Examples described include studies focused on maintaining or restoring function, improving quality of life and emotional well-being, and reducing symptoms across the full cancer experience (from active treatment through long-term survivorship).
What specific research topics are suggested as competitive under this award?
Competitive applications may examine areas such as treatment toxicity and supportive care strategies, psychological distress and anxiety, palliative or supportive care interventions, educational or decision-support tools, and approaches addressing cognitive issues linked to cancer or its therapies.
Does the opportunity encourage research related to behavioral and social functioning?
Yes. It encourages research on how behavioral and social functioning relates to cancer initiation, progression, detection, treatment, and rehabilitation, including studies aimed at improving mental health and cancer-related outcomes in defined populations.
What does the program mean by a focus on "real-world outcomes"?
The program emphasizes impact on outcomes that matter in practice, with a clear pathway to changing care or survivorship outcomes. The award is not intended for incremental work or purely exploratory ideas that do not show how they could translate into meaningful improvements.
Is purely exploratory research without a clear pathway to impact a good fit?
No. The PWSA is not meant for purely exploratory ideas without a clear pathway to changing care or survivorship outcomes.
What level of methodological detail do reviewers expect?
Reviewers expect proposals to clearly describe the overall architecture of the research approach, define study populations, and provide an appropriate statistical rationale aligned with the research question. The emphasis is on methodologically strong, interpretable studies.
What are the expectations for questionnaires or survey tools?
If questionnaires or survey tools are used, they should be described in enough detail to support how results will be interpreted and to justify why the measures are appropriate for the target population and outcomes.
Is preliminary data required for all applications?
No. Preliminary data expectations depend on whether the project includes active recruitment of human subjects.
When is preliminary data required?
If an application proposes prospective recruitment for a pilot clinical trial, preliminary data are required.
When is preliminary data not strictly required?
For studies that do not involve active recruitment, preliminary data are not strictly required. However, the proposal must still present a strong foundation supported by solid reasoning and relevant literature to demonstrate credibility and the likelihood of informative results.
Is patient advocate participation required?
Yes. A distinctive and non-negotiable requirement is patient advocate participation. Every application must include at least one cancer patient advocate as an integral member of the research team.
Who can serve as the required patient advocate?
The advocate can be someone living with cancer, a survivor with no evidence of disease, or a family member/caregiver.
Does the patient advocate need to be connected to an organization?
Yes. The advocate should be connected to a cancer advocacy organization, knowledgeable about current cancer issues, and aligned with the FY24 PRCRP Topic Area(s) being studied.
What does "integral member of the research team" mean for the patient advocate role?
The advocate is expected to be actively and continuously involved across planning and implementation, including shaping the research question, influencing study design, participating in oversight, and contributing to evaluation and interpretation.
Is it enough for the patient advocate to attend occasional meetings?
No. The opportunity explicitly notes that periodic attendance at meetings is not enough; the advocate role should be embedded into the project so patient priorities and practical impact remain central throughout.
Does the award support research focused on caregivers and family members?
Yes. Core issues may include psychosocial support for patients and those close to them, including family members and caregivers.
How many awards are anticipated?
The anticipated number of awards is six.
What is the application deadline?
The original closing date provided is July 26, 2024.
Is eligibility restricted?
Eligibility is listed as unrestricted.
Is there a stated award ceiling?
The award ceiling is not specified in the provided details.
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| DoD Peer Reviewed Cancer, Career Development Award- Scholar Option Apply for HT942524PRCRPCDASO Funding Number: HT942524PRCRPCDASO Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Cancer, Impact Award Apply for HT942524PRCRPIPA Funding Number: HT942524PRCRPIPA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Peer Reviewed Cancer, Idea Award Apply for HT942524PRCRPIA Funding Number: HT942524PRCRPIA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer, Physician Research Award Apply for HT942524PCRPPRA Funding Number: HT942524PCRPPRA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer, Early Investigator Research Award Apply for HT942524PCRPEIRA Funding Number: HT942524PCRPEIRA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer, Exploration - Hypothesis Development Award Apply for HT942524PCRPEHDA Funding Number: HT942524PCRPEHDA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer, Idea Development Award Apply for HT942524PCRPIDA Funding Number: HT942524PCRPIDA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Prostate Cancer, Implementation Science Award Apply for HT942524PCRPISA Funding Number: HT942524PCRPISA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DOD Duchenne Muscular Dystrophy, Clinical/Translational Research Award Apply for HT942524DMDRPCTRA Funding Number: HT942524DMDRPCTRA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD, Melanoma, Melanoma Academy Scholar Award Apply for HT942524MRPMASA Funding Number: HT942524MRPMASA Agency: Dept. of the Army -- USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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