Opportunity Information: Apply for RFA DK 25 023

The National Institutes of Health (NIH), through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), is soliciting applications to continue the Hematology Central Coordinating Center (HCCC) for the NIDDK Hematology Centers Program. This opportunity is issued as a cooperative agreement (U24) under Funding Opportunity Number RFA-DK-25-023, with an application due date of March 18, 2025. The HCCC is designed to function as the organizational and operational hub for a network of 4 to 5 Cooperative Centers of Excellence in Hematology (CCEHs) and, beyond that internal network role, to serve as a national resource for the broader nonmalignant hematology research community. The scientific focus across the overall Program is firmly centered on nonmalignant hematologic diseases and on understanding normal hematopoiesis, with the larger purpose of strengthening multidisciplinary research efforts in these areas.

The core expectation for the HCCC is to provide central administrative, logistical, and communications support that enables the Hematology Centers Program to operate as a cohesive, collaborative enterprise rather than as a set of disconnected sites. In practice, this coordinating function typically includes organizing governance and committee activities, facilitating cross-center interactions, supporting consistent policies and procedures, and ensuring that information flows efficiently among the CCEHs and NIDDK. The HCCC is also expected to support communications that extend outward to the broader research community, reinforcing the Program's role as a national focal point for nonmalignant hematology research coordination, awareness, and engagement.

A major required component of the HCCC is the operation of a Pilot and Feasibility Program. Through this function, the coordinating center will manage a process to solicit, review, select, and oversee pilot research studies intended to generate early data, launch new collaborative directions, and position investigators for larger-scale projects and future funding. The intent is to use pilot support strategically to accelerate promising ideas, encourage innovation, and fill gaps where modest, targeted funding can unlock bigger research opportunities. While the HCCC administers this program, it is expected to do so in a way that complements and strengthens the broader network of CCEHs and aligns with NIDDK priorities in nonmalignant hematology and hematopoiesis.

This funding opportunity is explicitly labeled "Clinical Trial Not Allowed," meaning applicants should propose activities that do not meet the NIH definition of a clinical trial. The work is expected to remain within permissible research and coordination activities under the U24 mechanism, such as program management, resource and network coordination, communications infrastructure, and pilot support that does not constitute an NIH-defined clinical trial.

Eligibility is broad across U.S.-based organizations and governmental entities. Eligible applicants include state, county, city or township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education as specified in the listing); for-profit organizations other than small businesses; and small businesses. The announcement also highlights additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. Foreign organizations are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible under this NOFO.

Only one award is expected to be made. The opportunity is categorized under the NIH assistance listing (CFDA) number 93.847, and it falls within the broader activity category of health (listed alongside food and nutrition/health). The award ceiling is not specified in the provided source data, so prospective applicants would need to consult the full NOFO text for budget parameters, project period details, and any cost limitations or expectations tied to the cooperative agreement structure.

  • The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Continuation of the NIDDK Hematology Central Coordinating Center (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
  • This funding opportunity was created on 2024-12-16.
  • Applicants must submit their applications by 2025-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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