Opportunity Information: Apply for 72067423RFA00003

USAID South Africa (USAID-Pretoria) released a funding opportunity titled "Achieving and Sustaining HIV/TB Epidemic Control in the KwaZulu-Natal Province" (Funding Opportunity Number 72067423RFA00003) to support longer, healthier lives in KwaZulu-Natal by helping the province achieve and maintain control of the HIV and TB epidemics. The opportunity is structured as a cooperative agreement, which typically means the awardee would implement programming with substantial involvement from USAID during planning, execution, monitoring, and adaptation. The activity sits in the health sector (CFDA 98.001) and was posted on October 24, 2022, with an original closing date of January 17, 2023 at 9:00 AM Pretoria local time.

At its core, the grant is designed to push KwaZulu-Natal closer to sustained epidemic control by focusing on three connected strategic objectives. First, it aims to close remaining gaps to HIV epidemic control, which generally refers to finding and addressing the populations, locations, or service delivery steps where people are still being missed across the HIV prevention, testing, treatment, and viral suppression pathway. Second, it emphasizes sustaining health gains through strengthened and more resilient health systems, signaling that the work is not only about short-term program outputs but also about improving the underlying systems that keep HIV and TB services functioning effectively over time. Third, it seeks to leverage partnerships beyond the formal health sector by working with communities, civil society, traditional structures, and the private sector to improve service delivery and client outcomes, reflecting the reality that lasting epidemic control depends on trust, access, demand for services, and supportive local networks.

The geographic focus is explicitly targeted to three high HIV-burden districts in KwaZulu-Natal: Harry Gwala, King Cetshwayo, and Ugu. At the same time, USAID notes that this focus could shift as epidemiological patterns change or as the Government of South Africa and the U.S. Government adjust priorities, which implies that the implementing partner should be prepared for data-driven geographic targeting and periodic realignment of resources. This kind of language often points to an expectation that the awardee will use surveillance and program performance data to adapt interventions, concentrate efforts where the need is greatest, and stay aligned with national and donor strategies.

In terms of scale, the opportunity lists an award ceiling of $104,000,000 and anticipates making a single award. That combination suggests a large, multi-year flagship implementation mechanism intended to consolidate programming under one primary recipient, likely with a network of subpartners to cover district-level implementation, community engagement, and specialized technical areas. Eligibility is listed broadly as "Others" with clarification referenced in an additional eligibility field (not provided in the excerpt), which commonly means a range of organization types may apply depending on the detailed eligibility language in the full announcement.

Overall, this opportunity is aimed at driving measurable HIV/TB outcomes in high-burden districts while also reinforcing the systems and partnerships needed to keep those gains in place. The emphasis on closing gaps, strengthening resilience, and leveraging community and private-sector partnerships indicates an approach that combines targeted clinical and public health interventions with broader health system improvements and community-centered delivery models, all implemented in coordination with South African government priorities and evolving epidemic trends.

  • The Agency for International Development, South Africa USAID-Pretoria in the health sector is offering a public funding opportunity titled "Achieving and Sustaining HIV/TB Epidemic Control in the KwaZulu-Natal Province Achieving and Sustaining HIV/TB Epidemic Control in the KwaZulu-Natal Province" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001.
  • This funding opportunity was created on Oct 24, 2022.
  • Applicants must submit their applications by Jan 17, 2023 January 17, 2023, 0900AM Pretoria Local Time. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $104,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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